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Raw Letrozole powder (112809-51-5)

November 8, 2018
SKU: 112809-51-5
5.00 out of 5 based on 1 customer rating
(1 customer review)
  • Letrozole (Femara) is a drug prescribed for the treatment of postmenopausal women with hormone receptive positive early breast cancer or who have been treated with tamoxifen (Nolvadex). Side effects, drug interactions, and pregnancy information should be reviewed prior to taking this medication.

 


Status: In Mass Production
Unit: 25kg/Drum

Raw Letrozole powder (112809-51-5) video

 

Raw Letrozole powder (112809-51-5) Description

Raw Letrozole powder is an oral non-steroidal aromatase inhibitor, brand name is Femara. It is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Raw Letrozole powder is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Raw Letrozole powder decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Raw Letrozole powder blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and Raw Letrozole powder does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.

Raw Letrozole powder has shown to reduce estrogen levels by 98 percent while raising testosterone levels. The anti-estrogen action of Raw Letrozole powder is preferred by athletes and bodybuilders for use during a steroid cycle to reduce bloating due to excess water retention and prevent the formation of gynecomastia related breast tissue that is a side effect of some anabolic steroids.

 

Raw Letrozole powder (112809-51-5) Specifications

Product Name Raw Letrozole powder
Chemical Name Femara; ,4′-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile; Letrozol
Brand Name Femara
Drug Class aromatase inhibitor
CAS Number 112809-51-5
InChIKey HPJKCIUCZWXJDR-UHFFFAOYSA-N
Molecular Formula C17H11N5
Molecular Weight 285.31 g/mol
Monoisotopic Mass 285.101 g/mol
Melting Point  184-185 °C
Freezing Point No data available
Biological Half-Life 2 days
Color While or off-while powder
Solubility  Water Solubility 0.0799 mg/mL
Storage Temperature  -20°C Freezer
Application 1. used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause.

2. bodybuilding

 

What is Raw Letrozole powder (112809-51-5)?

Letrozole is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

Raw Letrozole powder (112809-51-5) works

Letrozole lowers the levels of the female sex hormone oestrogen in the body. Oestrogen stimulates some breast cancers to grow. These breast cancers are called hormone sensitive or hormone receptor positive. Letrozole can stop or slow the growth of these cancers.

Letrozole only works in women who have had their menopause.

After the menopause, women don’t produce oestrogen from their ovaries. But they still produce a small amount by using an enzyme called aromatase which turns other sex hormones called androgens into oestrogen. This change happens mainly in fatty tissue, muscle and the skin. Letrozole is a type of drug called an aromatase inhibitor. It blocks aromatase so that it can’t change androgens into oestrogen.

Raw Letrozole powder (112809-51-5) Dosage

The recommended dose of Femara is one 2.5 mg tablet administered once a day, without regard to meals.

Raw Letrozole powder (112809-51-5) benefits

Two large studies have shown the benefits of Femara.

The international BIG 1-98 trial, started in 1998, compared Femara to tamoxifen after surgery in postmenopausal women diagnosed with hormone-receptor-positive, early-stage breast cancer. The results showed that Femara was better than tamoxifen for:

* Increasing the time before the cancer comes back in those who experience recurrence

* Reducing the risk of the cancer spreading to other parts of the body

The MA-17 study, conducted in Canada, looked at whether taking Femara for 5 years AFTER taking tamoxifen for 5 years (for a total of 10 years of hormonal therapy) could lower the risk of the cancer coming back in postmenopausal women diagnosed with hormone-receptor-positive, early-stage breast cancer. The results showed that Femara:

* Reduced the risk of the cancer coming back

* Reduced the risk of the cancer spreading to another part of the body

compared to not taking Femara after 5 years of tamoxifen.

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1 review for Raw Letrozole powder (112809-51-5)
  1. 5 out of 5

    :

    The product LETROZOLE POWDER is very useful.

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