Anastrozole powder (120511-73-1) Manufacturers & Suppliers - Factory

Raw Anastrozole powder (120511-73-1)

November 8, 2018
SKU: 120511-73-1
5.00 out of 5 based on 1 customer rating
(1 customer review)

Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

 


Status: In Mass Production
Unit: 25kg/Drum

Raw Anastrozole powder (120511-73-1) video

 

Raw Anastrozole powder (120511-73-1) Description

Raw Anastrozole powder, brand name is Arimidex. It is used with other treatments, such as surgery or radiation, to treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods). This medication is also used in women, who have experienced menopause, as a first treatment of breast cancer that has spread within the breast or to other areas of the body. This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Raw Anastrozole powder is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow.

Raw Anastrozole powder is a potent and selective non-steroidal aromatase inhibitor indicated for the treatment of advanced breast cancer in post-menopausal women with disease progression following tamoxifen therapy. Many breast cancers have estrogen receptors and growth of these tumors can be stimulated by estrogens. In post-menopausal women, the principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues, such as adipose tissue, with further conversion of estrone to estradiol. Many breast cancers also contain aromatase; the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. Raw Anastrozole powder is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.

 

Raw Anastrozole powder (120511-73-1) Specifications

Product Name Raw Anastrozole powder
Chemical Name ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE, Anastrozol
Brand Name Arimidex
Drug Class non-steroidal aromatase inhibitor
CAS Number 120511-73-1
InChIKey YBBLVLTVTVSKRW-UHFFFAOYSA-N
Molecular Formula C17H19N5
Molecular Weight 293.374 g/mol
Monoisotopic Mass 293.164 g/mol
Melting Point  130.14 °C
Freezing Point No data available
Biological Half-Life 50 hours
Color White powder
Solubility  water solubility 0.5 mg/mL
Storage Temperature  RT
Application For adjuvant treatment of hormone receptor positive breast cancer , as well as hormonal treatment of advanced breast cancer in post-menopausal women. Has also been used to treat pubertal gynecomastia and McCune-Albright syndrome.

 

What is Raw Anastrozole powder (120511-73-1)?

Anastrozole is a nonsteroidal inhibitor of aromatase which effectively blocks estrogen synthesis in postmenopausal women and is used as therapy of estrogen receptor positive breast cancer. Anastrozole has been associated with a low rate of serum enzyme elevations during therapy and rare instances of clinically apparent liver injury.

How Raw Anastrozole powder (120511-73-1) works

Anastrozole works by reducing the amount of oestrogen made in the body.

Some breast cancers are stimulated to grow by the hormone oestrogen. These are known as oestrogen receptor positive or ER+ breast cancers.

Anastrozole belongs to a group of drugs called aromatase inhibitors.

Raw Anastrozole powder (120511-73-1) Dosage

Recommended Dose:

The dose of ARIMIDEX is one 1 mg tablet taken once a day. For patients with advanced breast cancer, ARIMIDEX should be continued until tumor progression. ARIMIDEX can be taken with or without food.

For adjuvant treatment of early breast cancer in postmenopausal women, the optimal duration of therapy is unknown. In the ATAC trial, ARIMIDEX was administered for five years.

No dosage adjustment is necessary for patients with renal impairment or for elderly patients.

Raw Anastrozole powder (120511-73-1) benefits

The ATAC study found that 5 years of Arimidex is better than 5 years of tamoxifen as the first hormonal therapy for postmenopausal women with early-stage, hormone-receptor-positive breast cancer. Arimidex is better than tamoxifen for:

* Increasing the time before the cancer comes back in those who experience recurrence

* Reducing the risk of the cancer spreading to other parts of the body

* Reducing the risk of a new cancer developing in the other breast

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1 review for Raw Anastrozole powder (120511-73-1)
  1. 5 out of 5

    :

    The product ANASTROZOLE POWDER is very useful.

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