Raw Pregabalin powder (148553-50-8) Manufacturer - Buyaas

Pregabalin powder (148553-50-8)

June 25, 2019

Pregabalin powder (148553-50-8) is mainly used for treat Seizures; Neuropathic pain; Anxiety disorders. It’s belongs to a class of drugs called anticonvulsants.

 


Status: In Mass Production
Unit: 25kg/Drum

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Pregabalin powder (148553-50-8) Description

1. What is Pregabalin powder?

Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults. Some off-label uses of pregabalin include, restless leg syndrome, migraine, social phobia, panic disorder, mania, bipolar disorder, and alcohol withdrawal.

2. How Pregabalin powder works?

Pregabalin belongs to a class of drugs called anticonvulsants. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

It isn’t known exactly how pregabalin works. It’s believed to work by calming the damaged or overactive nerves in your body that may cause pain or seizures.

3. Pregabalin powder dosage

Usual Adult Dose for Diabetic Neuropathy:

-Initial dose: 50 mg orally 3 times a day

-Titration: The dose may be increased to 100 mg orally 3 times a day within 1 week based on efficacy and tolerability

-Maximum dose: 100 mg orally 3 times a day in patients with a creatinine clearance of at least 60 mL/min

Comment:

-This drug may be taken with or without food.

Use: Management of neuropathic pain associated with diabetic peripheral neuropathy

Usual Adult Dose for Postherpetic Neuralgia:

-Initial dose: 75 mg orally 2 times a day OR 50 mg orally 3 times a day

-Titration: The dose may be increased to 100 mg orally 3 times a day within 1 week based on efficacy and tolerability

-Maintenance dose: 75 to 150 mg orally 2 times a day OR 50 to 100 mg orally 3 times a day (150 to 300 mg/day) in patients with a creatinine clearance of at least 60 mL/min

-Maximum dose: Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day and who are able to tolerate this drug, may be treated with up to 300 mg orally 2 times a day or 200 mg orally 3 times a day (due to the dose-dependent adverse effects and the higher rate of treatment discontinuation due to adverse events, dosing above 300 mg/day should be reserved only for those patients who have ongoing pain and are tolerating 300 mg daily)

Comment:

-This drug may be taken with or without food.

Use: Management of postherpetic neuralgia

Usual Adult Dose for Epilepsy:

-Initial dose: 75 mg orally 2 times a day OR 50 mg orally 3 times a day

-Maintenance dose: 150 mg/day to 600 mg/day (the total daily dose should be divided and given either 2 or 3 times a day)

-Maximum dose: 600 mg/day in 2 or 3 divided doses based on individual patient response and tolerability

Comments:

-This drug may be taken with or without food.

-The efficacy of add-on therapy in patients taking gabapentin has not been evaluated in controlled trials; therefore, dosing recommendations for the use of this combination cannot be offered.

Use: Adjunctive therapy for adult patients with partial onset seizures

Usual Adult Dose for Fibromyalgia:

-Initial dose: 75 mg orally 2 times a day (150 mg/day)

-Titration: The dose may be increased to 150 mg orally 2 times a day (300 mg/day) within 1 week based on efficacy and tolerability

-Maintenance dose: 300 to 450 mg/day in 2 divided doses

-Maximum dose: Patients who do not experience sufficient benefit with 300 mg/day may be further increased to 225 mg orally 2 times a day (450 mg/day)

Comments:

-This drug may be taken with or without food.

Use: Management of fibromyalgia

Although Pregabalin powder was also studied at 600 mg/day, there is no evidence that this dose confers additional benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions, treatment with doses above 450 mg/day is not recommended.

Usual Adult Dose for Neuropathic Pain:

-Initial dose: 75 mg orally 2 times a day

-Titration: The dose may be increased to 150 mg orally 2 times a day within 1 week based on efficacy and tolerability

-Maintenance dose: 150 to 600 mg/day in divided doses

-Maximum dose: Patients who do not experience sufficient pain relief after 2 to 3 weeks of treatment with 150 mg orally 2 times a day and who tolerate this drug may be treated with up to 300 mg orally 2 times a day

Comments:

-This drug may be taken with or without food.

Use: Neuropathic pain associated with spinal cord injury

4. Buy Pregabalin powder from Buyaas.com

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1. Our products are produced under cGMP and the quality can be tracked.
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Pregabalin powder (148553-50-8) Specifications

Product Name Pregabalin
Chemical Name (S)-3-(Aminomethyl)-5-methylhexanoic acid
Brand Name Lyrica, others
Drug Class Anticonvulsants, Other; Analgesics, Other; Fibromyalgia Agents
CAS Number 148553-50-8
InChIKey AYXYPKUFHZROOJ-ZETCQYMHSA-N
Molecular Formula C8H17NO2
Molecular Weight 159.229
Monoisotopic Mass 159.1259 g/mol
Melting Point  186-188ºC
Boiling Point 274.0±23.0 °C at 760 mmHg
Biological Half-Life 6.3–11.5 hours
Color White powder
Solubility  Soluble in DMSO
Storage Temperature  0 – 4 C for short term (days to weeks), or -20 C for long term (months).
Application Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.

 


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1 review for Pregabalin powder (148553-50-8)
  1. :

    The product Pregabalin powder is very useful.

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