Raw Tadalafil (Cialis) powder (171596-29-5) video
Raw Tadalafil (Cialis) powder (171596-29-5) Description
1.What is Tadalafil powder?
Tadalafil powder, sold under the brand name Cialis powder among others, is a medication used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. It is a tablet taken by mouth. Onset is typically within half an hour and the duration is up to 36 hours.
Tadalafil powder, also known as IC351, is PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis powder, and under the name Adcirca for the treatment of pulmonary arterial hypertension.
2.How Tadalafil powder works
Penile erection occurs when the penis fills with blood. This happens because the blood vessels that bring blood flow to the penis dilate, increasing the blood supply. At the same time, the blood vessels that remove blood from the penis contract. The blood accumulates in the penis, causing an erection.
When a man is sexually stimulated, nitric oxide is released into the penis. Nitric oxide enables the production of cGMP, which controls the dilation and contraction of the blood vessels that carry blood to and from the penis.
Another substance, PDE5, destroys cGMP. When this occurs, the blood vessels return to their normal size, and the erection ends. Tadalafil powder stops PDE5 from destroying cGMP. This causes the erection to last for longer.
The muscles of the arteries in the walls of the lungs also contain PDE5, which is why the same drug can also help with pulmonary hypertension treatment.
Cialis powder Uses
Cialis powder comes in yellow, film-coated and almond-shaped tablets in 5, 10 and 20 milligram (mg) doses.
Patients with erectile dysfunction can take Cialis powder as needed, but it should not be taken more frequently than once every 24 hours.
For the medication to work, a man needs to be sexually aroused. The drug does not provide an erection without sexual stimulation.
A first dose is 10 milligrams (mg) at least 30 minutes before sexual activity. Dosage can then be adjusted depending on how the individual responds. The maximum is 20 mg as a single dose.
The patient should take no more than one dose in 24 hours, but a daily dose of 10 mg to 20 mg is not recommended. This is because a portion of the drug remains in the system for at least 24 hours.
Patients who expect to be sexually active at least twice a week can take a daily dose of 5 mg, and this may be reduced to 2.5 mg once daily, depending on the individual reaction.
Tadalafil powder for erectile dysfunction is only for use by adults aged 18 years and above.
Raw Tadalafil (Cialis) powder (171596-29-5) Specifications
|Product Name||Tadalafil (Cialis) powder|
|Brand Name||IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis|
|Drug Class||PDE5 inhibitor|
|Monoisotopic Mass||389.1376 g/mol|
|Melting Point||301-302 °C|
|Boiling Point||679.1±55.0 °C at 760 mmHg|
|Biological Half-Life||36 hours|
|Solubility||Soluble in DMSO, not in water|
|Storage Temperature||0 – 4 C for short term (days to weeks), or -20 C for long term (months)|
|Application||Tadalafil powder under the name of Cialis powder is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.|