Raw 17-Methyltestosterone powder (58-18-4) video
Raw 17-Methyltestosterone powder (58-18-4) Description
Raw 17-Methyltestosterone powder is a synthetic, orally activeanabolic-androgenic steroid (AAS) which is used in the treatment of androgen deficiency in males and for a number of other indications.Such as to delay puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women.
Raw 17-Methyltestosterone powder is also a methylated synthetic androgen receptor agonist with anabolic effects. Raw 17-Methyltestosterone powder, mimicking testosterone, binds to cytosolic androgen receptors, and the subsequent nuclear transfer of the ligand-receptor complex induces transcription initiation of androgen responsive genes. The gene products are responsible for normal growth and development of male sex organs and secondary sex characteristics. The agent also causes retention of nitrogen, sodium, potassium, phosphorus, as well as calcium.
Raw 17-Methyltestosterone powder (58-18-4) Specifications
|Product Name||Raw 17-Methyltestosterone powder|
|Chemical Name||RU-24400;NSC-9701;17α-Methyltestosterone; 17α-Methylandrost-4-en-17β-ol-3-one|
|Brand Name||Android, Metandren,Testred|
|Drug Class||Androgen; Anabolic steroid|
|Monoisotopic Mass||302.225 g/mol.l|
|Melting Point||162-168 °C(lit.)|
|Boiling point:||383.47°C (rough estimate)|
|Biological Half-Life||approximately 3 hours (range 2.5–3.5 hours)|
|Solubility||H2O: ≤0.5 mg/mL|
|Application||Medical use: Methyltestosterone is or has been used in the treatment of delayed puberty, hypogonadism, cryptorchidism, and erectile dysfunction in males, and in low doses to treat menopausal symptoms (specifically for osteoporosis, hot flashes, and to increase libido and energy), postpartum breast pain and engorgement, and breast cancer in women|
What is Raw 17-Methyltestosterone powder (58-18-4)?
17-Methyltestosterone, a synthetic derivative of testosterone, is an androgen and anabolic steroid (AAS) medication. It is mainly used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women (1-3). It appears as white or creamy white crystals or powder, which is soluble in various organic sol vents but is practically insoluble in water. It should be subject to oral administration.
Methyltestosterone was first discovered in 1935 and was introduced for medical use in 1936. It was synthesized shortly after the discovery of testosterone, being one of the first synthetic AAS drug. 17-Methyltestosterone, beyond its medical function, can also be used to improve physique and performance.
How Raw 17-Methyltestosterone powder (58-18-4) works
17-Methyltestosterone take effects through two main mechanisms: activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors.
17-Methyltestosterone can enter into the target tissue cells, binding to the androgen receptor, or being reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly, yielding a even stronger androgenic potency. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA, which is called hormone response elements (HREs). This process regulates the transcriptional activity of various genes, further producing the androgen effects.
Raw 17-Methyltestosterone powder (58-18-4) Dosage
17-Methyltestosterone is administered orally. The suggested dosage varies depending on the age, sex, and diagnosis of the individual patient. Dosage is adjusted according to the patient’s response and the appearance of adverse reactions. Replacement therapy in androgen-deficient males usually demands 10 to 50 mg of 17-Methyltestosterone daily. However, the chronological and skeletal ages must be taken into consideration both in determining the initial dose and in adjusting the dose. Doses used in the treatment of the delayed puberty generally are in the lower range of that given above, and for a limited duration, for example 4 to 6 months. For the treatment of women breast cancer, the dosage of 17-Methyltestosterone in females is from 50-200 mg daily.
Raw 17-Methyltestosterone powder (58-18-4) Benefits
17-Methyltestosterone powder can treat various symptoms such as hypogonadism, cryptorchidism, delayed puberty, and erectile dysfunction in males, and in low doses to treat menopausal symptoms (specifically for osteoporosis, hot flashes, and to increase libido and energy), postpartum breast pain and engorgement.
It is also used in women to treat breast cancer, swelling due to pregnancy, and with the addition of estrogen it can treat symptoms of menopause. It has also been used in combination with esterified estrogens for the treatment of moderate to severe vasomotor symptoms associated with menopause in females.
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